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It has >30-fold selectivity over other HDACs
InChi: InChI=1S/C21H17F3N4/c22-21(23
Muller Kobold AC
for 3 months) reduces active MMP-9 in untreated HT mice in a dose-dependent manner
Asimadoline 60312 It has >30-fold selectivity overAsimadoline (EMD 61753) is an orally active, selective and peripherally active opioid agonist with IC50s of 5. 6 nM (guinea pig) and 1. 2 nM (human recombinant). Asimadoline has low permeability across the blood brain barrier and has peripheral anti inflammatory actions. Asimadoline ameliorates allodynia in diabetic rats and has the potential for irritable bowel syndrome (IBS). Product information CAS Number: 153205 46 0 Molecular Weight: 414. 54
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